Abstract
Salbutamol and Clenbuterol are often used as β-agonists and illegally added in pig feed,resulting in pork contaminated and even leading athletes excessive excitability. Therefore,it has great significance for establishing a new rapid detection method of salbutamol and clenbuterol in pork. In this study,internal extraction electrospray ionization-mass spectrometry(iEESI-MS)technology was used for directly qualitative and quantitative analysis of salbutamol and clenbuterol in pork tissues without sample pretreatment. The results showed that this method had a high sensitivity to salbutamol and clenbuterol analysis with detection limits of(LOD)6. 2 and 9. 8 ng / kg,respectively,while the analysis time for detecting single sample and single index was less than 30 s. In a concentration range of 0. 01-1000 μg / kg,the logarithm of signal intensity(Y)and the logarithm of concentration(X)have a good linear relationship. This method has many advantages such as rapid analysis,low sample consumption and high sensitivity,which is ideal for rapid detection of trace salbutamol and clenbuterol.
Key Words: Internal extraction electrospray ionization;Salbutamol;Clenbuterol;β-Agonists;Organizational analysis
2016-Xiao Yipo-Chin J Anal Chem.pdf
